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2020-2016年||
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2015年-2011年||
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2010年-2006年||
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2000年-1996年||
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1995年-1986年||
2010年
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Application of the Fc fusion format to generate tag-free bi-specific diabodies
Ryutaro Asano, Keiko Ikoma, Hiroko Kawaguchi, Yuna Ishiyama, Takeshi Nakanishi, Mitsuo Umetsu, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai
The FEBS Journal (2010) 277 (2), 477-487
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Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells
Wook-Dong Kim, Miwako Tokunaga, Hiroyuki Ozaki, Takuya Ishibashi, Kohsuke Honda, Hiroyuki Kajiura, Kazuhito Fujiyama, Ryutaro Asano, Izumi Kumagai, Takeshi Omasa and Hisao Ohtake
Applied Microbiology and Biotechnology (2010) 85 (3), 535-542
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Selection of DNA Aptamer against Prostate Specific Antigen using a Genetic Algorithm and Application to Sensing
Nasa Savory, Koichi Abe, Koji Sode and Kazunori Ikebukuro
Biosensors and Bioelectronics (2010) 26 (4), 1386-1391
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Constructing an Improved Pyrroloquinoline Quinone Glucose Dehydrogenase Binding Aptamer for Enzyme Labeling
Koichi Abe, Koji Sode and Kazunori Ikebukuro
Biotechnology Letters (2010) 32 (9), 1293-1298
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Engineering of Dye-mediated Dehydrogenase Property of Fructosyl Amino Acid Oxidases by Site-directed Mutagenesis Studies of its Putative Proton Relay System
Seungsu Kim, Eri Nibe, Stefano Ferri, Wakako Tsugawa and Koji Sode
Biotechnology Letters (2010) 32 (8), 1123-1129
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Wireless Monitoring of Blood Glucose Levels in Flatfish with a Needle Biosensor
Hideaki Endo, Eiji Takahashi, Masataka Murata, Hitoshi Ohnuki, Huifeng Ren, Wakako Tsugawa and Koji Sode
Fisheries Science (2010) 76 (4), 687-694
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Protein-protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information
Mitsuo Umetsu, Takeshi Nakanishi, Ryutaro Asano, Takamitsu Hattori and Izumi Kumagai
The FEBS Journal (2010) 277 (9), 2009-2014
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Target cell-restricted apoptosis induction by 528scFv-TRAIL fusion protein specific for human EGFR and expressed in Escherichia coli
Adel Bardan, Ryutaro Asano, Makoto Nakayama, Yasuhiro Watanabe, Takeshi Nakanishi, Mitsuo Umetsu, Hiroki Hayashi, Yu Katayose, Michiaki Unno and Izumi Kumagai
International Journal of Oncology (2010) 36 (5), 1229-1234
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Motif-based Search for a Novel Fructosyl Peptide Oxidase from Genome Databases
Seungsu Kim, Stefano Ferri, Wakako Tsugawa, Kazushige Mori and Koji Sode
Biotechnology and Bioengineering (2010) 106 (3), 358-366
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Functional Expression of Phanerochaete chrysosporium Cellobiose Dehydrogenase Flavin Domain
Desriani, Stefano Ferri and Koji Sode
Biotechnology Letters (2010) 32 (6), 855-859
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Screening of DNA aptamer which binds to alpha-synuclein
Kaori Tsukakoshi, Ryuichi Harada, Koji Sode and Kazunori Ikebukuro
Biotechnology Letters (2010) 32 (5), 643-648
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The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein
Jihoon Kim, Ryuichi Harada, Masaki Kobayashi, Natsuki Kobayashi and Koji Sode
Molecular Neurodegeneration (2010) 5 (20)
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Enzyme Fuel Cell for Cellulolytic Sugar Conversion Employing FAD Glucose Dehydrogenase and Carbon Cloth Electrode Based on Direct Electron Transfer Principle
Desriani, Takuya Hanashi, Tomohiko Yamazaki, Wakako Tsugawa and Koji Sode
The Open Electrochemistry Journal (2010) 2 (6)-10
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Amino Acid Substitution at the Substrate-binding Subsite Alters the Specificity of the Phanerochaete chrysosporium cellobiose Dehydrogenase
Desriani, Stefano Ferri and Koji Sode
Biochemical and Biophysical Research Communication (2010) 391 (2), 1246-1250
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Screening and Improvement of an Anti-VEGF DNA Aptamer
Yoshihiko Nonaka, Koji Sode and Kazunori Ikebukuro
Molecules (2010) 15 (1), 215-225
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Pyrroloquinoline Quinone Inhibits the Fibrillation of Amyloid Proteins
Jihoon Kim, Masaki Kobayashi, Makoto Fukuda, Daisuke Ogasawara, Natsuki Kobayashi, Sungwoong Han, Chikashi Nakamura, Masaki Inada, Chisato Miyaura, Kazunori Ikebukuro and Koji Sode
Prion (2010) 4 (1), 26-31
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Integration of PEGylation and refolding for renaturation of recombinant proteins from insoluble aggregates produced in bacteria - Application to a single-chain Fv fragment
Izumi Kumagai, Ryutaro Asano, Takeshi Nakanishi, Kentaro Hashikami, Sho Tanaka, Adel Badran, Hideaki Sanada and Mitsuo Umetsu
Journal of Bioscience and Bioengineering (2010) 109 (5), 447-452
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Highly Enhanced Cytotoxicity of a Dimeric Bispecific Diabody, the hEx3 Tetrabody
Ryutaro Asano, Keiko Ikoma, Yukiko Sone, Hiroko Kawaguchi, Shintaro Taki, Hiroki Hayashi, Takashi Nakanishi, Mitsuo Umetsu, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai
Journal of Biological Chemistry (2010) 285 (27), 20844-20849
2009年
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Selection of DNA aptamers against insulin and construction of an aptameric enzyme subunit for insulin sensing
Wataru Yoshida, Eriko Mochizuki, Madoka Takase, Hijiri Hasegawa, Yo Morita, Hiroki Yamazaki, Koji Sode and Kazunori Ikebukuro
Biosensors and Bioelectronics (2009) 24 (5), 1116-1120
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BioCapacitor-A novel category of biosensor
Takuya Hanashi?, Tomohiko Yamazaki?, Wakako Tsugawa, Stefano Ferri, Daisuke Nakayama, Masamitsu Tomiyama, Kazunori Ikebukuro and Koji Sode
Biosensors and Bioelectronics (2009) 24 (7), 1837-1842 ?: Contributed equally
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Detection system based on the conformational change in an aptamer and its application to simple bound/free separation
Daisuke Ogasawara, Naomi S. Hachiya, Kiyotoshi Kaneko, Koji Sode and Kazunori Ikebukuro
Biosensors and Bioelectronics (2009) 24 (5), 1372-1376
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An Aptamer-Based Bound/Free Separation System for Protein Detection
Mieko Fukasawa, Wataru Yoshida, Hiroki Yamazaki, Koji Sode and Kazunori Ikebukuro
Electroanalysis (2009) 21 (11), 1297-1302
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The effect of amino acid substitution in the imperfect repeat sequences of alpha-synuclein on fibrillation
Ryuichi Harada, Natsuki Kobayashi, Jihoon Kim, Chikashi Nakamura, Sung-Woong Han, Kazunori Ikebukuro and Koji Sode
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2009) 1792 (10), 998-1003
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Kinetic Mechanism and Inhibitor Characterization of WNK1 Kinase
Yukiko I. Yagi, Koichi Abe, Kazunori Ikebukuro and Koji Sode
Biochemistry (2009) 48 (43), 10255-10266
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Zn finger-based direct detection system for PCR products of Salmonella spp. and the Influenza A virus
Yuko Osawa, Kazunori Ikebukuro and Koji Sode
Biotechnology Letters (2009) 31 (5), 725-733
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DNA Aptamers that Bind to PQQGDH as an Electrochemical Labeling Tool
Yuko Osawa, Madoka Takase, Koji Sode and Kazunori Ikeukuro
Electroanalysis (2009) 21 (11), 1303-1308
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Wireless enzyme sensor system for real-time monitoring of blood glucose levels in fish
Hideaki Endo, Yuki Yonemori, Kyoko Hibi, Huifeng Ren, Tetsuhito Hayashi, Wakako Tsugawa and Koji Sode
Biosensors and Bioelectronics (2009) 24 (5), 1417-1423
- Review:
Review of Fructosyl Amino Acid Oxidase Engineering Research: A Glimpse into the Future of Hemoglobin A1c Biosensing
Stefano Ferri, Seungsu Kim, Wakako Tsugawa and Koji Sode
Journal of Diabetes Science and Technology (2009) 3 (3), 585-592
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The construction of a glucose-sensing luciferase
Atsushi Taneoka, Akane Sakaguchi-Mikami, Tomohiko Yamazaki, Wakako Tsugawa and Koji Sode
Biosensors and Bioelectronics (2009) 25 (1), 76-81
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Cumulative effect of amino acid substitution for the development of fructosyl valine-specific fructosyl amine oxidase
Seungsu Kim, Seiji Miura, Stefano Ferri, Wakako Tsugawa and Koji Sode
Enzyme and Microbial Technology (2009) 44 (1), 52-56
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Electrochemical Detection of Epidermal Growth Factor Receptors on a Single Living Cell Surface by Scanning Electrochemical Microscopy
Yasufumi Takahashi, Takeshi Miyamoto, Hitoshi Shiku, Ryutaro Asano, Tomoyuki Yasukawa, Izumi Kumagai and Tomokazu Matsue
Analytical Chemistry (2009). 81 (7), 2785-2790
2008年
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Improvement of Aptamer Affinity by Dimerization
Hijiri Hasegawa?, Ken-ichi Taira?, Koji Sode and Kazunori Ikebukuro
Sensors (2008) 8 (2), 1090-1098 ?: Contributed equally
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Selection of DNA aptamers against VEGF165 using a protein competitor and the aptamer blotting method
Hijiri Hasegawa, Koji Sode and Kazunori Ikebukuro
Biotechnology Letters (2008) 30 (5), 829-834
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Label-free homogeneous detection of immunoglobulin E by an aptameric enzyme subunit
Wataru Yoshida, Koji Sode and Kazunori Ikebukuro
Biotechnology Letters (2008) 30 (3), 421-425
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The simple and rapid detection of specific PCR products from bacterial genomes using Zn finger proteins
Yuko Osawa, Kazunori Ikebukuro, Hiroaki Motoki, Takafumi Matsuo, Michio Horiuchi and Koji Sode
Nucleic Acids Research (2008) 36 (11), e68
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Aptameric enzyme subunit for homogeneous DNA sensing
Kazunori Ikebukuro, Wataru Yoshida and Koji Sode
Biotechnology Letters (2008) 30 (2), 243-252
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Zinc finger protein-based detection system of PCR products for pathogen diagnosis
Yuko Osawa, Hiroaki Motoki, Takafumi Matsuo, Michio Horiuchi, Koji Sode and Kazunori Ikebukuro
Nucleic Acids Symposium Series (2008) 52 (1), 23-24
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Aggregation and Fibrillation Study of alpha-synuclein Under Applied Voltage
Yuko Osawa, Kazunori Ikebukuro, Natsuki Kobayashi, Sung Woong Han, Chikashi Nakamura and Koji Sode
Electrochemistry (2008) 76 (8), 614-618
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Development of fructosyl amine oxidase specific to fructosyl valine by site-directed mutagenesis
Seiji Miura, Stefano Ferri, Wakako Tsugawa, Seungsu Kim and Koji Sode
Protein Engineering, Design and Selection (2008) 21 (4), 233-239
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Wireless Biosensor System for Real-Time Cholesterol Monitoring in Fish
Yohei Yoneyama, Yuki Yonemori, Koji Sode, Wakako Tsugawa, Tetsuhito Hayashi, Huifeng Ren and Hideaki Endo
ECS Meeting Abstracts (2008) 2, 2834
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Needle Biosensor for Continuous Blood Glucose Monitoring in Flatfish
Eiji Takahashi, Koji Sode, Wakako Tsugawa, Huifeng Ren, Tetsuhito Hayashi and Hideaki Endo
ECS Meeting Abstracts (2008) 2, 1470
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Direct Electron Transfer Type Continuous Glucose Monitoring System with Miniaturized Electrode
Hitomi Shimizu, Wakako Tsugawa, Hideaki Endo and Koji Sode
ECS Meeting Abstracts (2008) 2, 1505
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Propionate Sensor Using Coenzyme-A Transferase and Acyl-CoA Oxidase
Sode Koji, Tsugawa Wakako, Aoyagi Minoru, Rajashekhara Eranna and Watanabe Kazuya
Protein and Peptide Letters (2008) 15 (8), 779-781
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Thermodynamic Consequences of Mutations in Vernier Zone Residues of a Humanized Anti-human Epidermal Growth Factor Receptor Murine Antibody, 528
Koki Makabe, Takeshi Nakanishi, Kouhei Tsumoto, Yoshikazu Tanaka, Hidemasa Kondo, Mitsuo Umetsu, Yukiko Sone, Ryutaro Asano and Izumi Kumagai
The Journal of Biological Chemistry (2008) 283 (2), 1156-1166
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Diabody-based Recombinant Formats of Humanized IgG-like Bispecific Antibody With Effective Retargeting of Lymphocytes to Tumor Cells
Asano Ryutaro, Kawaguchi Hiroko, Watanabe Yasuhiro, Nakanishi Takeshi, Umetsu Mitsuo, Hayashi Hiroki, Katayose Yu, Unno Michiaki, Kudo Toshio and Kumagai Izumi
Journal of Immunotherapy (2008) 31 (8), 752-761
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Preferential heterodimerization of a bispecific diabody based on a humanized anti-EGFR antibody 528
Ryutaro Asano, Yukiko Sone, Keiko Ikoma, Hiroki Hayashi, Takeshi Nakanishi, Mitsuo Umetsu, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai
Protein Engineering, Design and Selection (2008) 21 (10), 596-603
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Grafting of material-binding function into antibodies: Functionalization by peptide grafting
Takamitsu Hattori, Mitsuo Umetsu, Takeshi Nakanishi, Kouhei Tsumoto, Satoshi Ohara, Hiroya Abe, Makio Naito, Ryutaro Asano, Tadafumi Adschiri and Izumi Kumagai
Biochemical and Biophysical Research Communications (2008) 365 (4), 751-757
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Characterize Cell Function using Scanning Electrochemical Optical Microscopy with Tip-Sample Distance Regulation
Yasufumi Takahashi, Takeshi Miyamoto, Tatsuya Murata, Hitoshi Shiku, Ryutaro Asano, Tomoyuki Yasukawa, Izumi Kumagai and Tomokazu Matsue
ECS Meeting Abstracts (2008) 2, 1490
2007年
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Peptide ligand screening of α-synuclein aggregation modulators by In silico panning
Koichi Abe, Natsuki Kobayashi, Koji Sode and Kazunori Ikebukuro
BMC Bioinformatics (2007) 8, 451
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In silico panning for a non-competitive peptide inhibitor
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunori Ikebukuro and Koji Sode
BMC Bioinformatics (2007) 8, 11
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Screening of DNA Aptamer Against Mouse Prion Protein by Competitive Selection
Daisuke Ogasawara, Hijiri Hasegawa, Kiyotoshi Kaneko, Koji Sode and Kazunori Ikebukuro
Prion (2007) 1 (4), 248-254
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Stopped-flow system with ozonizer for the estimation of low biochemical oxygen demand in environmental samples
Gab-Joo Chee, Yoko Nomura, Kazunori Ikebukuro and Isao Karube
Biosensors and Bioelectronics (2007) 22 (12), 3092-3098
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Selection and characterization of DNA aptamers against VEGF165 with aptamer blotting method and its application
Kazunori Ikebukuro, Hijiri Hasegawa and Koji Sode
Nucleic Acids Symposium Series (2007) 51 (1), 399-400
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Aptameric enzyme subunit for homogeneous protein sensing
Wataru Yoshida, Koji Sode and Kazunori Ikebukuro
Nucleic Acids Symposium Series (2007) 51 (1), 99-100
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Selection of DNA aptamers that inhibit enzymatic activity of PQQGDH and its application
Kazunori Ikebukuro, Madoka Takase and Koji Sode
Nucleic Acids Symposium Series (2007) 51 (1), 403-404
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Specific detection of PCR product from Legionella pneumophila strainPhiladelphia1 using zinc finger protein Sp2
Kazunori Ikebukuro, Takenori Kumagai, Hiroaki Motoki, Yuko Osawa, Takafumi Matuo, Michio Horiuchi and Koji Sode
Nucleic Acids Symposium Series (2007) 51 (1), 285-286
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Construction of target molecule sensing system using aptameric enzyme subunit based on PQQGDH activity
Kazunori Ikebukuro, Yo Morita, Wataru Yoshida and Koji Sode
Nucleic Acids Symposium Series (2007) 51 (1), 401-402
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A novel wireless glucose sensor employing direct electron transfer principle based enzyme fuel cell
Noriko Kakehi, Tomohiko Yamazaki, Wakako Tsugawa and Koji Sode
Biosensors and Bioelectronics (2007) 22 (9-10), 2250-2255
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Novel fluorescent sensing system for alpha-fructosyl amino acids based on engineered fructosyl amino acid binding protein
Akane Sakaguchi, Stefano Ferri, Wakako Tsugawa and Koji Sode
Biosensors and Bioelectronics (2007) 22 (9-10), 1993-1938
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High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma
Norihiko Akamatsu, Yasuaki Yamada, Hiroo Hasegawa, Koki Makabe, Ryutaro Asano, Izumi Kumagai, Ken Murata, Yoshitaka Imaizumi, Kunihiro Tsukasaki, Kazuto Tsuruda, Kazuyuki Sugahara, Sunao Atogami, Katsunori Yanagihara and Shimeru Kamihira
Cancer Letters (2007) 256 (2), 196-206
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Highly Effective Recombinant Format of a Humanized IgG-like Bispecific Antibody for Cancer Immunotherapy with Retargeting of Lymphocytes to Tumor Cells
Ryutaro Asano, Yasuhiro Watanabe, Hiroko Kawaguchi, Hidesuke Fukazawa, Takeshi Nakanishi, Mitsuo Umetsu, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai
The Journal of Biological Chemistry (2007) 282 (38), 27659-27665
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Electrochemical screening of recombinant protein solubility in Escherichia coli using scanning electrochemical microscopy (SECM)
Kuniaki Nagamine, Shiho Onodera, Ai Kurihara, Tomoyuki Yasukawa, Hitoshi Shiku, Ryutaro Asano, Izumi Kumagai and Tomokazu Matsue
Biotechnology and Bioengineering (2007) 96 (5), 1008-1013
2006年
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Pyrroloquinoline quinone (PQQ) prevents fibril formation of alpha-synuclein
Masaki Kobayashi, Jihoon Kim, Natsuki Kobayashi, Sungwoong Han, Chikashi Nakamura, Kazunori Ikebukuro and Koji Sode
Biochemical and Biophysical Research Communications (2006) 349 (3), 1139-1144
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Aptameric Enzyme Subunit for Biosensing Based on Enzymatic Activity Measurement
Wataru Yoshida, Koji Sode and Kazunori Ikebukuro
Analytical Chemistry (2006) 78 (10), 3296-3303
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Homogeneous DNA sensing using enzyme-inhibiting DNA aptamers
Wataru Yoshida, Koji Sode and Kazunori Ikebukuro
Biochemical and Biophysical Research Communications (2006) 348 (1), 245-252
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Aptamer selection based on inhibitory activity using an evolution-mimicking algorithm
Takahisa Noma and Kazunori Ikebukuro
Biochemical and Biophysical Research Communications (2006) 347 (1), 226-231
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A screening method for DNA aptamers that bind to a specific, unidentified protein in tissue samples
Takahisa Noma, Kazunori Ikebukuro, Koji Sode, Takuya Ohkubo, Yuji Sakasegawa and Naomi Hachiya
Biotechnology Letters (2006) 28 (17), 1377-1381
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Analysis of the evolution of the thrombin-inhibiting DNA aptamers using a genetic algorithm
Kazunori Ikebukuro, Wataru Yoshida, Takahisa Noma and Koji Sode
Biotechnology Letters (2006) 28 (23), 1933-1937
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Characterization and application of aptamers for Taq DNA polymerase selected using an evolution-mimicking algorithm
Takahisa Noma, Koji Sode and Kazunori Ikebukuro
Biotechnology Letters (2006) 28 (23), 1939-1944
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Analysis of DNA and Zinc finger interactions using mechanical force spectroscopy
Yanyan Wang, Shin-ichiro Oyokawa, Sung Woong Han, Wei Huang, Kazunori Ikebukuro, Chikashi Nakamura and Jun Miyake
NanoBiotechnology (2006) 2 (3-4), 87-93
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Active site analysis of fructosyl amine oxidase using homology modeling and site-directed mutagenesis
Seiji Miura, Stefano Ferri, Wakako Tsugawa, Seungsu Kim and Koji Sode
Biotechnology Letters (2006) 28 (23), 1895-1900
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Humanization of the Bispecific Epidermal Growth Factor Receptor × CD3 Diabody and Its Efficacy as a Potential Clinical Reagent
Ryutaro Asano, Yukiko Sone, Koki Makabe, Kouhei Tsumoto, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo and Izumi Kumagai
Clinical Cancer Research (2006) 12 (13), 4036-4042
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最新-2021年||
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2020-2016年||
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2015年-2011年||
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2010年-2006年||
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2005年-2001年||
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2000年-1996年||
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1995年-1986年||