GENE EXPRESSION AND REGULATION / z思唹kFおよび崙囮


The establishment of bacterial mutant strains for efficient production of high quality compound and products is crucial to industry. The environment hosts diverse bacterial species and strains of high industrial value and new strains are constantly been discovered. However, we still need techniques to manipulate these newly discovered strains to utilize them at their full potential. In our group, we aim on establishing techniques to efficiently exploit these strains by focusing on gene regulation and expression.

bIにとって互瞳|の晒栽麗やu瞳を紳糞弔防bするためには互b伏醸幄の_羨が音辛之です。徭隼順には謹謹Nの醸Nが伏連し、嶄にはbIの互い醸幄も謹くkされています。しかし、これら仟謎kされている醸幄を恷寄泙忙醵辰垢襪砲椀造燭兵斜gが箔められています。暴_のグル`プでは、z思唹kFおよび崙囮に醜泣を輝て、これらの醸幄の嗤神喘に叨羨つ室gの_羨を朕峺しています。


RESEARCH HIGHLIGHTS / 冩梢撹惚


PUBLICATION: Yokoi Y., et al., Molecules 27(24): 8944 (2022)

COLLABORATORS: Tanaka Lab, Mie University; Shibata Lab, Mie University and Muraoka Lab, Tokyo University of Agriculture and Technology
 
SUMMARY: Cell-penetrating peptide-peptide nucleic acid (CPP-PNA) conjugates were used in this research to characterize the function of hypothetical proteins within a hard-to-transform bacteria, Paenibacillus. In addition to the method being simple we successfully identified the carrageenase responsible for carageenan degradation in this bacterium.
 
云冩梢では弔邑^來ペプチド`ペプチド宰磨CPP-PNA嶷栽悶を旋喘し、伏悶蛍徨秘しにくい醸NであるPaenibacillusにし、隆岑タンパク|のC嬬盾苧を佩った。そのY惚、CPP-PNAの鮄辰砲茲螢織鵐僖|のC嬬盾苧が宴かつ儻堀に佩うことができ、Paenibacillusから仟たなカラギ`ナン蛍盾粛殆のkにも、った。