The establishment of bacterial mutant strains for efficient production of high quality compound and products is crucial to industry. The environment hosts diverse bacterial species and strains of high industrial value and new strains are constantly been discovered. However, we still need techniques to manipulate these newly discovered strains to utilize them at their full potential. In our group, we aim on establishing techniques to efficiently exploit these strains by focusing on gene regulation and expression.
PUBLICATION: Yokoi Y., et al., Molecules 27(24): 8944 (2022)
COLLABORATORS: Tanaka Lab, Mie University; Shibata Lab, Mie University and Muraoka Lab, Tokyo University of Agriculture and Technology
SUMMARY:Cell-penetrating peptide-peptide nucleic acid (CPP-PNA) conjugates were used in this research to characterize the function of hypothetical proteins within a hard-to-transform bacteria, Paenibacillus. In addition to the method being simple we successfully identified the carrageenase responsible for carageenan degradation in this bacterium.